Pregabalin is commonly used to treat nerve pain that may be associated with diabetes, herpes zoster (shingles), or injury to the spinal cord. It is also used to treat pain from fibromyalgia.
Pregabalin is also used in people with epilepsy to treat and prevent seizures, sometimes called convulsions.
Pregabalin may be used for other conditions as determined by your healthcare provider.
How does pregabalin work (mechanism of action)?
Pregabalin works in the central nervous system, or CNS, which includes the brain and spinal cord. Pregabalin may reduce the release of certain chemicals in the CNS that signal for pain.
It is believed that pregabalin also blocks abnormal electrical activity in the brain that causes seizures, which slows down the spread of seizures.
How is pregabalin supplied (dosage forms)?
Pregabalin is available as Lyrica, Lyrica CR, and generic pregabalin in the following dosage forms that are taken by mouth.
- 82.5 mg, 165 mg, 330 mg extended-release oral tablets
- 25 mg, 50 mg, 75 mg, 100 mg, 150 mg, 200 mg, 225 mg, 300 mg oral capsules
- 20 mg/mL oral solution
How should I store pregabalin?
Pregabalin should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it. Store in a cool, dry place.
Keep pregabalin in its original package.
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